This website is designed to inform physicians and provide them with probability scores for a number of outcomes. The models calculate the probability that certain side-effects, treatment outcomes and follow-up outcomes will occur. ptTheragnostic B.V. does not record prediction tool user outcome.

These models should only be used by physicians who are familiar with the complexity of treatment decisions in cancer treatment and should not be used directly by patients. We emphasize that the purpose of these models is to inform physicians and that the models should not be used for decision support. The models available on this website are not regarded as medical devices under the current MEDDEV guidelines from the European Commission.

The calculators which are provided are freeware for personal use only. They are not public domain software and may not be sold or used for commercial purposes. Permission to use and backup this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted. Permission to distribute this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted, provided that a reference to the following website and the entire License and Disclaimer are provided with all distributed copies: http://www.PredictCancer.org

The authors have made every effort to ensure that the information provided by this software is accurate and conforms to the methods described in the publications. However, the probability estimates published in the papers and which are estimated with these calculators may differ from those found in current clinical practice. In addition, a patient's prognosis may depend on other factors than those taken into account here. Thus, any decisions concerning patient care should not be based only on the use of these calculators, but should also take into account the patient's past history and other current patient and tumor characteristics. The model output supplements but does not substitute this individual clinical assessment. The creators of the PredictCancer website are not liable for clinical decision making that occurs between a physician and a patient.

As medical science is constantly changing and human error is always possible, the information contained in the prediction tools may be outdated, incomplete or incorrect. The authors, ptTheragnostic and MAASTRO clinic do not warrant the calculators' accuracy nor are they responsible for any omissions, errors or outcomes resulting from the use of these calculators. In no event shall either the authors, ptTheragnostic or MAASTRO clinic be liable to any party for any direct, indirect, special, incidental, or consequential damages, including lost profits, arising from the use of this software even if they have been advised of the possibility of such damage.

The authors, ptTheragnostic and MAASTRO clinic specifically disclaim any warranties, including but not limited to, the implied warranty of fitness for calculating the probabilities of outcomes for patients. The software provided hereunder is on an as is basis and neither the authors, ptTheragnostic nor the MAASTRO clinic have any obligations to provide maintenance, support, updates, enhancements or modifications.

By proceeding with use of the models, the user agrees that they have read and agreed with these terms.

This website is designed to inform physicians and provide them with probability scores for a number of outcomes. The models calculate the probability that certain side-effects, treatment outcomes and follow-up outcomes will occur. ptTheragnostic B.V. does not record prediction tool user outcome.

These models should only be used by physicians who are familiar with the complexity of treatment decisions in cancer treatment and should not be used directly by patients. We emphasize that the purpose of these models is to inform physicians and that the models should not be used for decision support. The models available on this website are not regarded as medical devices under the current MEDDEV guidelines from the European Commission.

The calculators which are provided are freeware for personal use only. They are not public domain software and may not be sold or used for commercial purposes. Permission to use and backup this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted. Permission to distribute this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted, provided that a reference to the following website and the entire License and Disclaimer are provided with all distributed copies: http://www.PredictCancer.org

The authors have made every effort to ensure that the information provided by this software is accurate and conforms to the methods described in the publications. However, the probability estimates published in the papers and which are estimated with these calculators may differ from those found in current clinical practice. In addition, a patient's prognosis may depend on other factors than those taken into account here. Thus, any decisions concerning patient care should not be based only on the use of these calculators, but should also take into account the patient's past history and other current patient and tumor characteristics. The model output supplements but does not substitute this individual clinical assessment. The creators of the PredictCancer website are not liable for clinical decision making that occurs between a physician and a patient.

As medical science is constantly changing and human error is always possible, the information contained in the prediction tools may be outdated, incomplete or incorrect. The authors, ptTheragnostic and MAASTRO clinic do not warrant the calculators' accuracy nor are they responsible for any omissions, errors or outcomes resulting from the use of these calculators. In no event shall either the authors, ptTheragnostic or MAASTRO clinic be liable to any party for any direct, indirect, special, incidental, or consequential damages, including lost profits, arising from the use of this software even if they have been advised of the possibility of such damage.

The authors, ptTheragnostic and MAASTRO clinic specifically disclaim any warranties, including but not limited to, the implied warranty of fitness for calculating the probabilities of outcomes for patients. The software provided hereunder is on an as is basis and neither the authors, ptTheragnostic nor the MAASTRO clinic have any obligations to provide maintenance, support, updates, enhancements or modifications.

By proceeding with use of the models, the user agrees that they have read and agreed with these terms.

This website is designed to inform physicians and provide them with probability scores for a number of outcomes. The models calculate the probability that certain side-effects, treatment outcomes and follow-up outcomes will occur. ptTheragnostic B.V. does not record prediction tool user outcome.

These models should only be used by physicians who are familiar with the complexity of treatment decisions in cancer treatment and should not be used directly by patients. We emphasize that the purpose of these models is to inform physicians and that the models should not be used for decision support. The models available on this website are not regarded as medical devices under the current MEDDEV guidelines from the European Commission.

The calculators which are provided are freeware for personal use only. They are not public domain software and may not be sold or used for commercial purposes. Permission to use and backup this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted. Permission to distribute this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted, provided that a reference to the following website and the entire License and Disclaimer are provided with all distributed copies: http://www.PredictCancer.org

The authors have made every effort to ensure that the information provided by this software is accurate and conforms to the methods described in the publications. However, the probability estimates published in the papers and which are estimated with these calculators may differ from those found in current clinical practice. In addition, a patient's prognosis may depend on other factors than those taken into account here. Thus, any decisions concerning patient care should not be based only on the use of these calculators, but should also take into account the patient's past history and other current patient and tumor characteristics. The model output supplements but does not substitute this individual clinical assessment. The creators of the PredictCancer website are not liable for clinical decision making that occurs between a physician and a patient.

As medical science is constantly changing and human error is always possible, the information contained in the prediction tools may be outdated, incomplete or incorrect. The authors, ptTheragnostic and MAASTRO clinic do not warrant the calculators' accuracy nor are they responsible for any omissions, errors or outcomes resulting from the use of these calculators. In no event shall either the authors, ptTheragnostic or MAASTRO clinic be liable to any party for any direct, indirect, special, incidental, or consequential damages, including lost profits, arising from the use of this software even if they have been advised of the possibility of such damage.

The authors, ptTheragnostic and MAASTRO clinic specifically disclaim any warranties, including but not limited to, the implied warranty of fitness for calculating the probabilities of outcomes for patients. The software provided hereunder is on an as is basis and neither the authors, ptTheragnostic nor the MAASTRO clinic have any obligations to provide maintenance, support, updates, enhancements or modifications.

By proceeding with use of the models, the user agrees that they have read and agreed with these terms.

This website is designed to inform physicians and provide them with probability scores for a number of outcomes. The models calculate the probability that certain side-effects, treatment outcomes and follow-up outcomes will occur. ptTheragnostic B.V. does not record prediction tool user outcome.

These models should only be used by physicians who are familiar with the complexity of treatment decisions in cancer treatment and should not be used directly by patients. We emphasize that the purpose of these models is to inform physicians and that the models should not be used for decision support. The models available on this website are not regarded as medical devices under the current MEDDEV guidelines from the European Commission.

The calculators which are provided are freeware for personal use only. They are not public domain software and may not be sold or used for commercial purposes. Permission to use and backup this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted. Permission to distribute this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted, provided that a reference to the following website and the entire License and Disclaimer are provided with all distributed copies: http://www.PredictCancer.org

The authors have made every effort to ensure that the information provided by this software is accurate and conforms to the methods described in the publications. However, the probability estimates published in the papers and which are estimated with these calculators may differ from those found in current clinical practice. In addition, a patient's prognosis may depend on other factors than those taken into account here. Thus, any decisions concerning patient care should not be based only on the use of these calculators, but should also take into account the patient's past history and other current patient and tumor characteristics. The model output supplements but does not substitute this individual clinical assessment. The creators of the PredictCancer website are not liable for clinical decision making that occurs between a physician and a patient.

As medical science is constantly changing and human error is always possible, the information contained in the prediction tools may be outdated, incomplete or incorrect. The authors, ptTheragnostic and MAASTRO clinic do not warrant the calculators' accuracy nor are they responsible for any omissions, errors or outcomes resulting from the use of these calculators. In no event shall either the authors, ptTheragnostic or MAASTRO clinic be liable to any party for any direct, indirect, special, incidental, or consequential damages, including lost profits, arising from the use of this software even if they have been advised of the possibility of such damage.

The authors, ptTheragnostic and MAASTRO clinic specifically disclaim any warranties, including but not limited to, the implied warranty of fitness for calculating the probabilities of outcomes for patients. The software provided hereunder is on an as is basis and neither the authors, ptTheragnostic nor the MAASTRO clinic have any obligations to provide maintenance, support, updates, enhancements or modifications.

By proceeding with use of the models, the user agrees that they have read and agreed with these terms.

This website is designed to inform physicians and provide them with probability scores for a number of outcomes. The models calculate the probability that certain side-effects, treatment outcomes and follow-up outcomes will occur. ptTheragnostic B.V. does not record prediction tool user outcome.

These models should only be used by physicians who are familiar with the complexity of treatment decisions in cancer treatment and should not be used directly by patients. We emphasize that the purpose of these models is to inform physicians and that the models should not be used for decision support. The models available on this website are not regarded as medical devices under the current MEDDEV guidelines from the European Commission.

The calculators which are provided are freeware for personal use only. They are not public domain software and may not be sold or used for commercial purposes. Permission to use and backup this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted. Permission to distribute this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted, provided that a reference to the following website and the entire License and Disclaimer are provided with all distributed copies: http://www.PredictCancer.org

The authors have made every effort to ensure that the information provided by this software is accurate and conforms to the methods described in the publications. However, the probability estimates published in the papers and which are estimated with these calculators may differ from those found in current clinical practice. In addition, a patient's prognosis may depend on other factors than those taken into account here. Thus, any decisions concerning patient care should not be based only on the use of these calculators, but should also take into account the patient's past history and other current patient and tumor characteristics. The model output supplements but does not substitute this individual clinical assessment. The creators of the PredictCancer website are not liable for clinical decision making that occurs between a physician and a patient.

As medical science is constantly changing and human error is always possible, the information contained in the prediction tools may be outdated, incomplete or incorrect. The authors, ptTheragnostic and MAASTRO clinic do not warrant the calculators' accuracy nor are they responsible for any omissions, errors or outcomes resulting from the use of these calculators. In no event shall either the authors, ptTheragnostic or MAASTRO clinic be liable to any party for any direct, indirect, special, incidental, or consequential damages, including lost profits, arising from the use of this software even if they have been advised of the possibility of such damage.

The authors, ptTheragnostic and MAASTRO clinic specifically disclaim any warranties, including but not limited to, the implied warranty of fitness for calculating the probabilities of outcomes for patients. The software provided hereunder is on an as is basis and neither the authors, ptTheragnostic nor the MAASTRO clinic have any obligations to provide maintenance, support, updates, enhancements or modifications.

By proceeding with use of the models, the user agrees that they have read and agreed with these terms.

This website is designed to inform physicians and provide them with probability scores for a number of outcomes. The models calculate the probability that certain side-effects, treatment outcomes and follow-up outcomes will occur. ptTheragnostic B.V. does not record prediction tool user outcome.

These models should only be used by physicians who are familiar with the complexity of treatment decisions in cancer treatment and should not be used directly by patients. We emphasize that the purpose of these models is to inform physicians and that the models should not be used for decision support. The models available on this website are not regarded as medical devices under the current MEDDEV guidelines from the European Commission.

The calculators which are provided are freeware for personal use only. They are not public domain software and may not be sold or used for commercial purposes. Permission to use and backup this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted. Permission to distribute this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted, provided that a reference to the following website and the entire License and Disclaimer are provided with all distributed copies: http://www.PredictCancer.org

The authors have made every effort to ensure that the information provided by this software is accurate and conforms to the methods described in the publications. However, the probability estimates published in the papers and which are estimated with these calculators may differ from those found in current clinical practice. In addition, a patient's prognosis may depend on other factors than those taken into account here. Thus, any decisions concerning patient care should not be based only on the use of these calculators, but should also take into account the patient's past history and other current patient and tumor characteristics. The model output supplements but does not substitute this individual clinical assessment. The creators of the PredictCancer website are not liable for clinical decision making that occurs between a physician and a patient.

As medical science is constantly changing and human error is always possible, the information contained in the prediction tools may be outdated, incomplete or incorrect. The authors, ptTheragnostic and MAASTRO clinic do not warrant the calculators' accuracy nor are they responsible for any omissions, errors or outcomes resulting from the use of these calculators. In no event shall either the authors, ptTheragnostic or MAASTRO clinic be liable to any party for any direct, indirect, special, incidental, or consequential damages, including lost profits, arising from the use of this software even if they have been advised of the possibility of such damage.

The authors, ptTheragnostic and MAASTRO clinic specifically disclaim any warranties, including but not limited to, the implied warranty of fitness for calculating the probabilities of outcomes for patients. The software provided hereunder is on an as is basis and neither the authors, ptTheragnostic nor the MAASTRO clinic have any obligations to provide maintenance, support, updates, enhancements or modifications.

By proceeding with use of the models, the user agrees that they have read and agreed with these terms.

This website is designed to inform physicians and provide them with probability scores for a number of outcomes. The models calculate the probability that certain side-effects, treatment outcomes and follow-up outcomes will occur. ptTheragnostic B.V. does not record prediction tool user outcome.

These models should only be used by physicians who are familiar with the complexity of treatment decisions in cancer treatment and should not be used directly by patients. We emphasize that the purpose of these models is to inform physicians and that the models should not be used for decision support. The models available on this website are not regarded as medical devices under the current MEDDEV guidelines from the European Commission.

The calculators which are provided are freeware for personal use only. They are not public domain software and may not be sold or used for commercial purposes. Permission to use and backup this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted. Permission to distribute this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted, provided that a reference to the following website and the entire License and Disclaimer are provided with all distributed copies: http://www.PredictCancer.org

The authors have made every effort to ensure that the information provided by this software is accurate and conforms to the methods described in the publications. However, the probability estimates published in the papers and which are estimated with these calculators may differ from those found in current clinical practice. In addition, a patient's prognosis may depend on other factors than those taken into account here. Thus, any decisions concerning patient care should not be based only on the use of these calculators, but should also take into account the patient's past history and other current patient and tumor characteristics. The model output supplements but does not substitute this individual clinical assessment. The creators of the PredictCancer website are not liable for clinical decision making that occurs between a physician and a patient.

As medical science is constantly changing and human error is always possible, the information contained in the prediction tools may be outdated, incomplete or incorrect. The authors, ptTheragnostic and MAASTRO clinic do not warrant the calculators' accuracy nor are they responsible for any omissions, errors or outcomes resulting from the use of these calculators. In no event shall either the authors, ptTheragnostic or MAASTRO clinic be liable to any party for any direct, indirect, special, incidental, or consequential damages, including lost profits, arising from the use of this software even if they have been advised of the possibility of such damage.

The authors, ptTheragnostic and MAASTRO clinic specifically disclaim any warranties, including but not limited to, the implied warranty of fitness for calculating the probabilities of outcomes for patients. The software provided hereunder is on an as is basis and neither the authors, ptTheragnostic nor the MAASTRO clinic have any obligations to provide maintenance, support, updates, enhancements or modifications.

By proceeding with use of the models, the user agrees that they have read and agreed with these terms.

This website is designed to inform physicians and provide them with probability scores for a number of outcomes. The models calculate the probability that certain side-effects, treatment outcomes and follow-up outcomes will occur. ptTheragnostic B.V. does not record prediction tool user outcome.

These models should only be used by physicians who are familiar with the complexity of treatment decisions in cancer treatment and should not be used directly by patients. We emphasize that the purpose of these models is to inform physicians and that the models should not be used for decision support. The models available on this website are not regarded as medical devices under the current MEDDEV guidelines from the European Commission.

The calculators which are provided are freeware for personal use only. They are not public domain software and may not be sold or used for commercial purposes. Permission to use and backup this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted. Permission to distribute this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted, provided that a reference to the following website and the entire License and Disclaimer are provided with all distributed copies: http://www.PredictCancer.org

The authors have made every effort to ensure that the information provided by this software is accurate and conforms to the methods described in the publications. However, the probability estimates published in the papers and which are estimated with these calculators may differ from those found in current clinical practice. In addition, a patient's prognosis may depend on other factors than those taken into account here. Thus, any decisions concerning patient care should not be based only on the use of these calculators, but should also take into account the patient's past history and other current patient and tumor characteristics. The model output supplements but does not substitute this individual clinical assessment. The creators of the PredictCancer website are not liable for clinical decision making that occurs between a physician and a patient.

As medical science is constantly changing and human error is always possible, the information contained in the prediction tools may be outdated, incomplete or incorrect. The authors, ptTheragnostic and MAASTRO clinic do not warrant the calculators' accuracy nor are they responsible for any omissions, errors or outcomes resulting from the use of these calculators. In no event shall either the authors, ptTheragnostic or MAASTRO clinic be liable to any party for any direct, indirect, special, incidental, or consequential damages, including lost profits, arising from the use of this software even if they have been advised of the possibility of such damage.

The authors, ptTheragnostic and MAASTRO clinic specifically disclaim any warranties, including but not limited to, the implied warranty of fitness for calculating the probabilities of outcomes for patients. The software provided hereunder is on an as is basis and neither the authors, ptTheragnostic nor the MAASTRO clinic have any obligations to provide maintenance, support, updates, enhancements or modifications.

By proceeding with use of the models, the user agrees that they have read and agreed with these terms.

This website is designed to inform physicians and provide them with probability scores for a number of outcomes. The models calculate the probability that certain side-effects, treatment outcomes and follow-up outcomes will occur. ptTheragnostic B.V. does not record prediction tool user outcome.

These models should only be used by physicians who are familiar with the complexity of treatment decisions in cancer treatment and should not be used directly by patients. We emphasize that the purpose of these models is to inform physicians and that the models should not be used for decision support. The models available on this website are not regarded as medical devices under the current MEDDEV guidelines from the European Commission.

The calculators which are provided are freeware for personal use only. They are not public domain software and may not be sold or used for commercial purposes. Permission to use and backup this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted. Permission to distribute this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted, provided that a reference to the following website and the entire License and Disclaimer are provided with all distributed copies: http://www.PredictCancer.org

The authors have made every effort to ensure that the information provided by this software is accurate and conforms to the methods described in the publications. However, the probability estimates published in the papers and which are estimated with these calculators may differ from those found in current clinical practice. In addition, a patient's prognosis may depend on other factors than those taken into account here. Thus, any decisions concerning patient care should not be based only on the use of these calculators, but should also take into account the patient's past history and other current patient and tumor characteristics. The model output supplements but does not substitute this individual clinical assessment. The creators of the PredictCancer website are not liable for clinical decision making that occurs between a physician and a patient.

As medical science is constantly changing and human error is always possible, the information contained in the prediction tools may be outdated, incomplete or incorrect. The authors, ptTheragnostic and MAASTRO clinic do not warrant the calculators' accuracy nor are they responsible for any omissions, errors or outcomes resulting from the use of these calculators. In no event shall either the authors, ptTheragnostic or MAASTRO clinic be liable to any party for any direct, indirect, special, incidental, or consequential damages, including lost profits, arising from the use of this software even if they have been advised of the possibility of such damage.

The authors, ptTheragnostic and MAASTRO clinic specifically disclaim any warranties, including but not limited to, the implied warranty of fitness for calculating the probabilities of outcomes for patients. The software provided hereunder is on an as is basis and neither the authors, ptTheragnostic nor the MAASTRO clinic have any obligations to provide maintenance, support, updates, enhancements or modifications.

By proceeding with use of the models, the user agrees that they have read and agreed with these terms.

This website is designed to inform physicians and provide them with probability scores for a number of outcomes. The models calculate the probability that certain side-effects, treatment outcomes and follow-up outcomes will occur. ptTheragnostic B.V. does not record prediction tool user outcome.

These models should only be used by physicians who are familiar with the complexity of treatment decisions in cancer treatment and should not be used directly by patients. We emphasize that the purpose of these models is to inform physicians and that the models should not be used for decision support. The models available on this website are not regarded as medical devices under the current MEDDEV guidelines from the European Commission.

The calculators which are provided are freeware for personal use only. They are not public domain software and may not be sold or used for commercial purposes. Permission to use and backup this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted. Permission to distribute this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted, provided that a reference to the following website and the entire License and Disclaimer are provided with all distributed copies: http://www.PredictCancer.org

The authors have made every effort to ensure that the information provided by this software is accurate and conforms to the methods described in the publications. However, the probability estimates published in the papers and which are estimated with these calculators may differ from those found in current clinical practice. In addition, a patient's prognosis may depend on other factors than those taken into account here. Thus, any decisions concerning patient care should not be based only on the use of these calculators, but should also take into account the patient's past history and other current patient and tumor characteristics. The model output supplements but does not substitute this individual clinical assessment. The creators of the PredictCancer website are not liable for clinical decision making that occurs between a physician and a patient.

As medical science is constantly changing and human error is always possible, the information contained in the prediction tools may be outdated, incomplete or incorrect. The authors, ptTheragnostic and MAASTRO clinic do not warrant the calculators' accuracy nor are they responsible for any omissions, errors or outcomes resulting from the use of these calculators. In no event shall either the authors, ptTheragnostic or MAASTRO clinic be liable to any party for any direct, indirect, special, incidental, or consequential damages, including lost profits, arising from the use of this software even if they have been advised of the possibility of such damage.

The authors, ptTheragnostic and MAASTRO clinic specifically disclaim any warranties, including but not limited to, the implied warranty of fitness for calculating the probabilities of outcomes for patients. The software provided hereunder is on an as is basis and neither the authors, ptTheragnostic nor the MAASTRO clinic have any obligations to provide maintenance, support, updates, enhancements or modifications.

By proceeding with use of the models, the user agrees that they have read and agreed with these terms.

This website is designed to inform physicians and provide them with probability scores for a number of outcomes. The models calculate the probability that certain side-effects, treatment outcomes and follow-up outcomes will occur. ptTheragnostic B.V. does not record prediction tool user outcome.

These models should only be used by physicians who are familiar with the complexity of treatment decisions in cancer treatment and should not be used directly by patients. We emphasize that the purpose of these models is to inform physicians and that the models should not be used for decision support. The models available on this website are not regarded as medical devices under the current MEDDEV guidelines from the European Commission.

The calculators which are provided are freeware for personal use only. They are not public domain software and may not be sold or used for commercial purposes. Permission to use and backup this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted. Permission to distribute this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted, provided that a reference to the following website and the entire License and Disclaimer are provided with all distributed copies: http://www.PredictCancer.org

The authors have made every effort to ensure that the information provided by this software is accurate and conforms to the methods described in the publications. However, the probability estimates published in the papers and which are estimated with these calculators may differ from those found in current clinical practice. In addition, a patient's prognosis may depend on other factors than those taken into account here. Thus, any decisions concerning patient care should not be based only on the use of these calculators, but should also take into account the patient's past history and other current patient and tumor characteristics. The model output supplements but does not substitute this individual clinical assessment. The creators of the PredictCancer website are not liable for clinical decision making that occurs between a physician and a patient.

As medical science is constantly changing and human error is always possible, the information contained in the prediction tools may be outdated, incomplete or incorrect. The authors, ptTheragnostic and MAASTRO clinic do not warrant the calculators' accuracy nor are they responsible for any omissions, errors or outcomes resulting from the use of these calculators. In no event shall either the authors, ptTheragnostic or MAASTRO clinic be liable to any party for any direct, indirect, special, incidental, or consequential damages, including lost profits, arising from the use of this software even if they have been advised of the possibility of such damage.

The authors, ptTheragnostic and MAASTRO clinic specifically disclaim any warranties, including but not limited to, the implied warranty of fitness for calculating the probabilities of outcomes for patients. The software provided hereunder is on an as is basis and neither the authors, ptTheragnostic nor the MAASTRO clinic have any obligations to provide maintenance, support, updates, enhancements or modifications.

By proceeding with use of the models, the user agrees that they have read and agreed with these terms.

This website is designed to inform physicians and provide them with probability scores for a number of outcomes. The models calculate the probability that certain side-effects, treatment outcomes and follow-up outcomes will occur. ptTheragnostic B.V. does not record prediction tool user outcome.

These models should only be used by physicians who are familiar with the complexity of treatment decisions in cancer treatment and should not be used directly by patients. We emphasize that the purpose of these models is to inform physicians and that the models should not be used for decision support. The models available on this website are not regarded as medical devices under the current MEDDEV guidelines from the European Commission.

The calculators which are provided are freeware for personal use only. They are not public domain software and may not be sold or used for commercial purposes. Permission to use and backup this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted. Permission to distribute this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted, provided that a reference to the following website and the entire License and Disclaimer are provided with all distributed copies: http://www.PredictCancer.org

The authors have made every effort to ensure that the information provided by this software is accurate and conforms to the methods described in the publications. However, the probability estimates published in the papers and which are estimated with these calculators may differ from those found in current clinical practice. In addition, a patient's prognosis may depend on other factors than those taken into account here. Thus, any decisions concerning patient care should not be based only on the use of these calculators, but should also take into account the patient's past history and other current patient and tumor characteristics. The model output supplements but does not substitute this individual clinical assessment. The creators of the PredictCancer website are not liable for clinical decision making that occurs between a physician and a patient.

As medical science is constantly changing and human error is always possible, the information contained in the prediction tools may be outdated, incomplete or incorrect. The authors, ptTheragnostic and MAASTRO clinic do not warrant the calculators' accuracy nor are they responsible for any omissions, errors or outcomes resulting from the use of these calculators. In no event shall either the authors, ptTheragnostic or MAASTRO clinic be liable to any party for any direct, indirect, special, incidental, or consequential damages, including lost profits, arising from the use of this software even if they have been advised of the possibility of such damage.

The authors, ptTheragnostic and MAASTRO clinic specifically disclaim any warranties, including but not limited to, the implied warranty of fitness for calculating the probabilities of outcomes for patients. The software provided hereunder is on an as is basis and neither the authors, ptTheragnostic nor the MAASTRO clinic have any obligations to provide maintenance, support, updates, enhancements or modifications.

By proceeding with use of the models, the user agrees that they have read and agreed with these terms.

This website is designed to inform physicians and provide them with probability scores for a number of outcomes. The models calculate the probability that certain side-effects, treatment outcomes and follow-up outcomes will occur. ptTheragnostic B.V. does not record prediction tool user outcome.

These models should only be used by physicians who are familiar with the complexity of treatment decisions in cancer treatment and should not be used directly by patients. We emphasize that the purpose of these models is to inform physicians and that the models should not be used for decision support. The models available on this website are not regarded as medical devices under the current MEDDEV guidelines from the European Commission.

The calculators which are provided are freeware for personal use only. They are not public domain software and may not be sold or used for commercial purposes. Permission to use and backup this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted. Permission to distribute this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted, provided that a reference to the following website and the entire License and Disclaimer are provided with all distributed copies: http://www.PredictCancer.org

The authors have made every effort to ensure that the information provided by this software is accurate and conforms to the methods described in the publications. However, the probability estimates published in the papers and which are estimated with these calculators may differ from those found in current clinical practice. In addition, a patient's prognosis may depend on other factors than those taken into account here. Thus, any decisions concerning patient care should not be based only on the use of these calculators, but should also take into account the patient's past history and other current patient and tumor characteristics. The model output supplements but does not substitute this individual clinical assessment. The creators of the PredictCancer website are not liable for clinical decision making that occurs between a physician and a patient.

As medical science is constantly changing and human error is always possible, the information contained in the prediction tools may be outdated, incomplete or incorrect. The authors, ptTheragnostic and MAASTRO clinic do not warrant the calculators' accuracy nor are they responsible for any omissions, errors or outcomes resulting from the use of these calculators. In no event shall either the authors, ptTheragnostic or MAASTRO clinic be liable to any party for any direct, indirect, special, incidental, or consequential damages, including lost profits, arising from the use of this software even if they have been advised of the possibility of such damage.

The authors, ptTheragnostic and MAASTRO clinic specifically disclaim any warranties, including but not limited to, the implied warranty of fitness for calculating the probabilities of outcomes for patients. The software provided hereunder is on an as is basis and neither the authors, ptTheragnostic nor the MAASTRO clinic have any obligations to provide maintenance, support, updates, enhancements or modifications.

By proceeding with use of the models, the user agrees that they have read and agreed with these terms.

This website is designed to inform physicians and provide them with probability scores for a number of outcomes. The models calculate the probability that certain side-effects, treatment outcomes and follow-up outcomes will occur. ptTheragnostic B.V. does not record prediction tool user outcome.

These models should only be used by physicians who are familiar with the complexity of treatment decisions in cancer treatment and should not be used directly by patients. We emphasize that the purpose of these models is to inform physicians and that the models should not be used for decision support. The models available on this website are not regarded as medical devices under the current MEDDEV guidelines from the European Commission.

The calculators which are provided are freeware for personal use only. They are not public domain software and may not be sold or used for commercial purposes. Permission to use and backup this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted. Permission to distribute this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted, provided that a reference to the following website and the entire License and Disclaimer are provided with all distributed copies: http://www.PredictCancer.org

The authors have made every effort to ensure that the information provided by this software is accurate and conforms to the methods described in the publications. However, the probability estimates published in the papers and which are estimated with these calculators may differ from those found in current clinical practice. In addition, a patient's prognosis may depend on other factors than those taken into account here. Thus, any decisions concerning patient care should not be based only on the use of these calculators, but should also take into account the patient's past history and other current patient and tumor characteristics. The model output supplements but does not substitute this individual clinical assessment. The creators of the PredictCancer website are not liable for clinical decision making that occurs between a physician and a patient.

As medical science is constantly changing and human error is always possible, the information contained in the prediction tools may be outdated, incomplete or incorrect. The authors, ptTheragnostic and MAASTRO clinic do not warrant the calculators' accuracy nor are they responsible for any omissions, errors or outcomes resulting from the use of these calculators. In no event shall either the authors, ptTheragnostic or MAASTRO clinic be liable to any party for any direct, indirect, special, incidental, or consequential damages, including lost profits, arising from the use of this software even if they have been advised of the possibility of such damage.

The authors, ptTheragnostic and MAASTRO clinic specifically disclaim any warranties, including but not limited to, the implied warranty of fitness for calculating the probabilities of outcomes for patients. The software provided hereunder is on an as is basis and neither the authors, ptTheragnostic nor the MAASTRO clinic have any obligations to provide maintenance, support, updates, enhancements or modifications.

By proceeding with use of the models, the user agrees that they have read and agreed with these terms.

This website is designed to inform physicians and provide them with probability scores for a number of outcomes. The models calculate the probability that certain side-effects, treatment outcomes and follow-up outcomes will occur. ptTheragnostic B.V. does not record prediction tool user outcome.

These models should only be used by physicians who are familiar with the complexity of treatment decisions in cancer treatment and should not be used directly by patients. We emphasize that the purpose of these models is to inform physicians and that the models should not be used for decision support. The models available on this website are not regarded as medical devices under the current MEDDEV guidelines from the European Commission.

The calculators which are provided are freeware for personal use only. They are not public domain software and may not be sold or used for commercial purposes. Permission to use and backup this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted. Permission to distribute this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted, provided that a reference to the following website and the entire License and Disclaimer are provided with all distributed copies: http://www.PredictCancer.org

The authors have made every effort to ensure that the information provided by this software is accurate and conforms to the methods described in the publications. However, the probability estimates published in the papers and which are estimated with these calculators may differ from those found in current clinical practice. In addition, a patient's prognosis may depend on other factors than those taken into account here. Thus, any decisions concerning patient care should not be based only on the use of these calculators, but should also take into account the patient's past history and other current patient and tumor characteristics. The model output supplements but does not substitute this individual clinical assessment. The creators of the PredictCancer website are not liable for clinical decision making that occurs between a physician and a patient.

As medical science is constantly changing and human error is always possible, the information contained in the prediction tools may be outdated, incomplete or incorrect. The authors, ptTheragnostic and MAASTRO clinic do not warrant the calculators' accuracy nor are they responsible for any omissions, errors or outcomes resulting from the use of these calculators. In no event shall either the authors, ptTheragnostic or MAASTRO clinic be liable to any party for any direct, indirect, special, incidental, or consequential damages, including lost profits, arising from the use of this software even if they have been advised of the possibility of such damage.

The authors, ptTheragnostic and MAASTRO clinic specifically disclaim any warranties, including but not limited to, the implied warranty of fitness for calculating the probabilities of outcomes for patients. The software provided hereunder is on an as is basis and neither the authors, ptTheragnostic nor the MAASTRO clinic have any obligations to provide maintenance, support, updates, enhancements or modifications.

By proceeding with use of the models, the user agrees that they have read and agreed with these terms.

This website is designed to inform physicians and provide them with probability scores for a number of outcomes. The models calculate the probability that certain side-effects, treatment outcomes and follow-up outcomes will occur. ptTheragnostic B.V. does not record prediction tool user outcome.

These models should only be used by physicians who are familiar with the complexity of treatment decisions in cancer treatment and should not be used directly by patients. We emphasize that the purpose of these models is to inform physicians and that the models should not be used for decision support. The models available on this website are not regarded as medical devices under the current MEDDEV guidelines from the European Commission.

The calculators which are provided are freeware for personal use only. They are not public domain software and may not be sold or used for commercial purposes. Permission to use and backup this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted. Permission to distribute this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted, provided that a reference to the following website and the entire License and Disclaimer are provided with all distributed copies: http://www.PredictCancer.org

The authors have made every effort to ensure that the information provided by this software is accurate and conforms to the methods described in the publications. However, the probability estimates published in the papers and which are estimated with these calculators may differ from those found in current clinical practice. In addition, a patient's prognosis may depend on other factors than those taken into account here. Thus, any decisions concerning patient care should not be based only on the use of these calculators, but should also take into account the patient's past history and other current patient and tumor characteristics. The model output supplements but does not substitute this individual clinical assessment. The creators of the PredictCancer website are not liable for clinical decision making that occurs between a physician and a patient.

As medical science is constantly changing and human error is always possible, the information contained in the prediction tools may be outdated, incomplete or incorrect. The authors, ptTheragnostic and MAASTRO clinic do not warrant the calculators' accuracy nor are they responsible for any omissions, errors or outcomes resulting from the use of these calculators. In no event shall either the authors, ptTheragnostic or MAASTRO clinic be liable to any party for any direct, indirect, special, incidental, or consequential damages, including lost profits, arising from the use of this software even if they have been advised of the possibility of such damage.

The authors, ptTheragnostic and MAASTRO clinic specifically disclaim any warranties, including but not limited to, the implied warranty of fitness for calculating the probabilities of outcomes for patients. The software provided hereunder is on an as is basis and neither the authors, ptTheragnostic nor the MAASTRO clinic have any obligations to provide maintenance, support, updates, enhancements or modifications.

By proceeding with use of the models, the user agrees that they have read and agreed with these terms.

This website is designed to inform physicians and provide them with probability scores for a number of outcomes. The models calculate the probability that certain side-effects, treatment outcomes and follow-up outcomes will occur. ptTheragnostic B.V. does not record prediction tool user outcome.

These models should only be used by physicians who are familiar with the complexity of treatment decisions in cancer treatment and should not be used directly by patients. We emphasize that the purpose of these models is to inform physicians and that the models should not be used for decision support. The models available on this website are not regarded as medical devices under the current MEDDEV guidelines from the European Commission.

The calculators which are provided are freeware for personal use only. They are not public domain software and may not be sold or used for commercial purposes. Permission to use and backup this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted. Permission to distribute this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted, provided that a reference to the following website and the entire License and Disclaimer are provided with all distributed copies: http://www.PredictCancer.org

The authors have made every effort to ensure that the information provided by this software is accurate and conforms to the methods described in the publications. However, the probability estimates published in the papers and which are estimated with these calculators may differ from those found in current clinical practice. In addition, a patient's prognosis may depend on other factors than those taken into account here. Thus, any decisions concerning patient care should not be based only on the use of these calculators, but should also take into account the patient's past history and other current patient and tumor characteristics. The model output supplements but does not substitute this individual clinical assessment. The creators of the PredictCancer website are not liable for clinical decision making that occurs between a physician and a patient.

As medical science is constantly changing and human error is always possible, the information contained in the prediction tools may be outdated, incomplete or incorrect. The authors, ptTheragnostic and MAASTRO clinic do not warrant the calculators' accuracy nor are they responsible for any omissions, errors or outcomes resulting from the use of these calculators. In no event shall either the authors, ptTheragnostic or MAASTRO clinic be liable to any party for any direct, indirect, special, incidental, or consequential damages, including lost profits, arising from the use of this software even if they have been advised of the possibility of such damage.

The authors, ptTheragnostic and MAASTRO clinic specifically disclaim any warranties, including but not limited to, the implied warranty of fitness for calculating the probabilities of outcomes for patients. The software provided hereunder is on an as is basis and neither the authors, ptTheragnostic nor the MAASTRO clinic have any obligations to provide maintenance, support, updates, enhancements or modifications.

By proceeding with use of the models, the user agrees that they have read and agreed with these terms.

This website is designed to inform physicians and provide them with probability scores for a number of outcomes. The models calculate the probability that certain side-effects, treatment outcomes and follow-up outcomes will occur. ptTheragnostic B.V. does not record prediction tool user outcome.

These models should only be used by physicians who are familiar with the complexity of treatment decisions in cancer treatment and should not be used directly by patients. We emphasize that the purpose of these models is to inform physicians and that the models should not be used for decision support. The models available on this website are not regarded as medical devices under the current MEDDEV guidelines from the European Commission.

The calculators which are provided are freeware for personal use only. They are not public domain software and may not be sold or used for commercial purposes. Permission to use and backup this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted. Permission to distribute this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted, provided that a reference to the following website and the entire License and Disclaimer are provided with all distributed copies: http://www.PredictCancer.org

The authors have made every effort to ensure that the information provided by this software is accurate and conforms to the methods described in the publications. However, the probability estimates published in the papers and which are estimated with these calculators may differ from those found in current clinical practice. In addition, a patient's prognosis may depend on other factors than those taken into account here. Thus, any decisions concerning patient care should not be based only on the use of these calculators, but should also take into account the patient's past history and other current patient and tumor characteristics. The model output supplements but does not substitute this individual clinical assessment. The creators of the PredictCancer website are not liable for clinical decision making that occurs between a physician and a patient.

As medical science is constantly changing and human error is always possible, the information contained in the prediction tools may be outdated, incomplete or incorrect. The authors, ptTheragnostic and MAASTRO clinic do not warrant the calculators' accuracy nor are they responsible for any omissions, errors or outcomes resulting from the use of these calculators. In no event shall either the authors, ptTheragnostic or MAASTRO clinic be liable to any party for any direct, indirect, special, incidental, or consequential damages, including lost profits, arising from the use of this software even if they have been advised of the possibility of such damage.

The authors, ptTheragnostic and MAASTRO clinic specifically disclaim any warranties, including but not limited to, the implied warranty of fitness for calculating the probabilities of outcomes for patients. The software provided hereunder is on an as is basis and neither the authors, ptTheragnostic nor the MAASTRO clinic have any obligations to provide maintenance, support, updates, enhancements or modifications.

By proceeding with use of the models, the user agrees that they have read and agreed with these terms.

This website is designed to inform physicians and provide them with probability scores for a number of outcomes. The models calculate the probability that certain side-effects, treatment outcomes and follow-up outcomes will occur. ptTheragnostic B.V. does not record prediction tool user outcome.

These models should only be used by physicians who are familiar with the complexity of treatment decisions in cancer treatment and should not be used directly by patients. We emphasize that the purpose of these models is to inform physicians and that the models should not be used for decision support. The models available on this website are not regarded as medical devices under the current MEDDEV guidelines from the European Commission.

The calculators which are provided are freeware for personal use only. They are not public domain software and may not be sold or used for commercial purposes. Permission to use and backup this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted. Permission to distribute this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted, provided that a reference to the following website and the entire License and Disclaimer are provided with all distributed copies: http://www.PredictCancer.org

The authors have made every effort to ensure that the information provided by this software is accurate and conforms to the methods described in the publications. However, the probability estimates published in the papers and which are estimated with these calculators may differ from those found in current clinical practice. In addition, a patient's prognosis may depend on other factors than those taken into account here. Thus, any decisions concerning patient care should not be based only on the use of these calculators, but should also take into account the patient's past history and other current patient and tumor characteristics. The model output supplements but does not substitute this individual clinical assessment. The creators of the PredictCancer website are not liable for clinical decision making that occurs between a physician and a patient.

As medical science is constantly changing and human error is always possible, the information contained in the prediction tools may be outdated, incomplete or incorrect. The authors, ptTheragnostic and MAASTRO clinic do not warrant the calculators' accuracy nor are they responsible for any omissions, errors or outcomes resulting from the use of these calculators. In no event shall either the authors, ptTheragnostic or MAASTRO clinic be liable to any party for any direct, indirect, special, incidental, or consequential damages, including lost profits, arising from the use of this software even if they have been advised of the possibility of such damage.

The authors, ptTheragnostic and MAASTRO clinic specifically disclaim any warranties, including but not limited to, the implied warranty of fitness for calculating the probabilities of outcomes for patients. The software provided hereunder is on an as is basis and neither the authors, ptTheragnostic nor the MAASTRO clinic have any obligations to provide maintenance, support, updates, enhancements or modifications.

By proceeding with use of the models, the user agrees that they have read and agreed with these terms.

This website is designed to inform physicians and provide them with probability scores for a number of outcomes. The models calculate the probability that certain side-effects, treatment outcomes and follow-up outcomes will occur. ptTheragnostic B.V. does not record prediction tool user outcome.

These models should only be used by physicians who are familiar with the complexity of treatment decisions in cancer treatment and should not be used directly by patients. We emphasize that the purpose of these models is to inform physicians and that the models should not be used for decision support. The models available on this website are not regarded as medical devices under the current MEDDEV guidelines from the European Commission.

The calculators which are provided are freeware for personal use only. They are not public domain software and may not be sold or used for commercial purposes. Permission to use and backup this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted. Permission to distribute this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted, provided that a reference to the following website and the entire License and Disclaimer are provided with all distributed copies: http://www.PredictCancer.org

The authors have made every effort to ensure that the information provided by this software is accurate and conforms to the methods described in the publications. However, the probability estimates published in the papers and which are estimated with these calculators may differ from those found in current clinical practice. In addition, a patient's prognosis may depend on other factors than those taken into account here. Thus, any decisions concerning patient care should not be based only on the use of these calculators, but should also take into account the patient's past history and other current patient and tumor characteristics. The model output supplements but does not substitute this individual clinical assessment. The creators of the PredictCancer website are not liable for clinical decision making that occurs between a physician and a patient.

As medical science is constantly changing and human error is always possible, the information contained in the prediction tools may be outdated, incomplete or incorrect. The authors, ptTheragnostic and MAASTRO clinic do not warrant the calculators' accuracy nor are they responsible for any omissions, errors or outcomes resulting from the use of these calculators. In no event shall either the authors, ptTheragnostic or MAASTRO clinic be liable to any party for any direct, indirect, special, incidental, or consequential damages, including lost profits, arising from the use of this software even if they have been advised of the possibility of such damage.

The authors, ptTheragnostic and MAASTRO clinic specifically disclaim any warranties, including but not limited to, the implied warranty of fitness for calculating the probabilities of outcomes for patients. The software provided hereunder is on an as is basis and neither the authors, ptTheragnostic nor the MAASTRO clinic have any obligations to provide maintenance, support, updates, enhancements or modifications.

By proceeding with use of the models, the user agrees that they have read and agreed with these terms.

This website is designed to inform physicians and provide them with probability scores for a number of outcomes. The models calculate the probability that certain side-effects, treatment outcomes and follow-up outcomes will occur. ptTheragnostic B.V. does not record prediction tool user outcome.

These models should only be used by physicians who are familiar with the complexity of treatment decisions in cancer treatment and should not be used directly by patients. We emphasize that the purpose of these models is to inform physicians and that the models should not be used for decision support. The models available on this website are not regarded as medical devices under the current MEDDEV guidelines from the European Commission.

The calculators which are provided are freeware for personal use only. They are not public domain software and may not be sold or used for commercial purposes. Permission to use and backup this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted. Permission to distribute this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted, provided that a reference to the following website and the entire License and Disclaimer are provided with all distributed copies: http://www.PredictCancer.org

The authors have made every effort to ensure that the information provided by this software is accurate and conforms to the methods described in the publications. However, the probability estimates published in the papers and which are estimated with these calculators may differ from those found in current clinical practice. In addition, a patient's prognosis may depend on other factors than those taken into account here. Thus, any decisions concerning patient care should not be based only on the use of these calculators, but should also take into account the patient's past history and other current patient and tumor characteristics. The model output supplements but does not substitute this individual clinical assessment. The creators of the PredictCancer website are not liable for clinical decision making that occurs between a physician and a patient.

As medical science is constantly changing and human error is always possible, the information contained in the prediction tools may be outdated, incomplete or incorrect. The authors, ptTheragnostic and MAASTRO clinic do not warrant the calculators' accuracy nor are they responsible for any omissions, errors or outcomes resulting from the use of these calculators. In no event shall either the authors, ptTheragnostic or MAASTRO clinic be liable to any party for any direct, indirect, special, incidental, or consequential damages, including lost profits, arising from the use of this software even if they have been advised of the possibility of such damage.

The authors, ptTheragnostic and MAASTRO clinic specifically disclaim any warranties, including but not limited to, the implied warranty of fitness for calculating the probabilities of outcomes for patients. The software provided hereunder is on an as is basis and neither the authors, ptTheragnostic nor the MAASTRO clinic have any obligations to provide maintenance, support, updates, enhancements or modifications.

By proceeding with use of the models, the user agrees that they have read and agreed with these terms.

This website is designed to inform physicians and provide them with probability scores for a number of outcomes. The models calculate the probability that certain side-effects, treatment outcomes and follow-up outcomes will occur. ptTheragnostic B.V. does not record prediction tool user outcome.

These models should only be used by physicians who are familiar with the complexity of treatment decisions in cancer treatment and should not be used directly by patients. We emphasize that the purpose of these models is to inform physicians and that the models should not be used for decision support. The models available on this website are not regarded as medical devices under the current MEDDEV guidelines from the European Commission.

The calculators which are provided are freeware for personal use only. They are not public domain software and may not be sold or used for commercial purposes. Permission to use and backup this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted. Permission to distribute this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted, provided that a reference to the following website and the entire License and Disclaimer are provided with all distributed copies: http://www.PredictCancer.org

The authors have made every effort to ensure that the information provided by this software is accurate and conforms to the methods described in the publications. However, the probability estimates published in the papers and which are estimated with these calculators may differ from those found in current clinical practice. In addition, a patient's prognosis may depend on other factors than those taken into account here. Thus, any decisions concerning patient care should not be based only on the use of these calculators, but should also take into account the patient's past history and other current patient and tumor characteristics. The model output supplements but does not substitute this individual clinical assessment. The creators of the PredictCancer website are not liable for clinical decision making that occurs between a physician and a patient.

As medical science is constantly changing and human error is always possible, the information contained in the prediction tools may be outdated, incomplete or incorrect. The authors, ptTheragnostic and MAASTRO clinic do not warrant the calculators' accuracy nor are they responsible for any omissions, errors or outcomes resulting from the use of these calculators. In no event shall either the authors, ptTheragnostic or MAASTRO clinic be liable to any party for any direct, indirect, special, incidental, or consequential damages, including lost profits, arising from the use of this software even if they have been advised of the possibility of such damage.

The authors, ptTheragnostic and MAASTRO clinic specifically disclaim any warranties, including but not limited to, the implied warranty of fitness for calculating the probabilities of outcomes for patients. The software provided hereunder is on an as is basis and neither the authors, ptTheragnostic nor the MAASTRO clinic have any obligations to provide maintenance, support, updates, enhancements or modifications.

By proceeding with use of the models, the user agrees that they have read and agreed with these terms.

This website is designed to inform physicians and provide them with probability scores for a number of outcomes. The models calculate the probability that certain side-effects, treatment outcomes and follow-up outcomes will occur. ptTheragnostic B.V. does not record prediction tool user outcome.

These models should only be used by physicians who are familiar with the complexity of treatment decisions in cancer treatment and should not be used directly by patients. We emphasize that the purpose of these models is to inform physicians and that the models should not be used for decision support. The models available on this website are not regarded as medical devices under the current MEDDEV guidelines from the European Commission.

The calculators which are provided are freeware for personal use only. They are not public domain software and may not be sold or used for commercial purposes. Permission to use and backup this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted. Permission to distribute this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted, provided that a reference to the following website and the entire License and Disclaimer are provided with all distributed copies: http://www.PredictCancer.org

The authors have made every effort to ensure that the information provided by this software is accurate and conforms to the methods described in the publications. However, the probability estimates published in the papers and which are estimated with these calculators may differ from those found in current clinical practice. In addition, a patient's prognosis may depend on other factors than those taken into account here. Thus, any decisions concerning patient care should not be based only on the use of these calculators, but should also take into account the patient's past history and other current patient and tumor characteristics. The model output supplements but does not substitute this individual clinical assessment. The creators of the PredictCancer website are not liable for clinical decision making that occurs between a physician and a patient.

As medical science is constantly changing and human error is always possible, the information contained in the prediction tools may be outdated, incomplete or incorrect. The authors, ptTheragnostic and MAASTRO clinic do not warrant the calculators' accuracy nor are they responsible for any omissions, errors or outcomes resulting from the use of these calculators. In no event shall either the authors, ptTheragnostic or MAASTRO clinic be liable to any party for any direct, indirect, special, incidental, or consequential damages, including lost profits, arising from the use of this software even if they have been advised of the possibility of such damage.

The authors, ptTheragnostic and MAASTRO clinic specifically disclaim any warranties, including but not limited to, the implied warranty of fitness for calculating the probabilities of outcomes for patients. The software provided hereunder is on an as is basis and neither the authors, ptTheragnostic nor the MAASTRO clinic have any obligations to provide maintenance, support, updates, enhancements or modifications.

By proceeding with use of the models, the user agrees that they have read and agreed with these terms.

This website is designed to inform physicians and provide them with probability scores for a number of outcomes. The models calculate the probability that certain side-effects, treatment outcomes and follow-up outcomes will occur. ptTheragnostic B.V. does not record prediction tool user outcome.

These models should only be used by physicians who are familiar with the complexity of treatment decisions in cancer treatment and should not be used directly by patients. We emphasize that the purpose of these models is to inform physicians and that the models should not be used for decision support. The models available on this website are not regarded as medical devices under the current MEDDEV guidelines from the European Commission.

The calculators which are provided are freeware for personal use only. They are not public domain software and may not be sold or used for commercial purposes. Permission to use and backup this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted. Permission to distribute this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted, provided that a reference to the following website and the entire License and Disclaimer are provided with all distributed copies: http://www.PredictCancer.org

The authors have made every effort to ensure that the information provided by this software is accurate and conforms to the methods described in the publications. However, the probability estimates published in the papers and which are estimated with these calculators may differ from those found in current clinical practice. In addition, a patient's prognosis may depend on other factors than those taken into account here. Thus, any decisions concerning patient care should not be based only on the use of these calculators, but should also take into account the patient's past history and other current patient and tumor characteristics. The model output supplements but does not substitute this individual clinical assessment. The creators of the PredictCancer website are not liable for clinical decision making that occurs between a physician and a patient.

As medical science is constantly changing and human error is always possible, the information contained in the prediction tools may be outdated, incomplete or incorrect. The authors, ptTheragnostic and MAASTRO clinic do not warrant the calculators' accuracy nor are they responsible for any omissions, errors or outcomes resulting from the use of these calculators. In no event shall either the authors, ptTheragnostic or MAASTRO clinic be liable to any party for any direct, indirect, special, incidental, or consequential damages, including lost profits, arising from the use of this software even if they have been advised of the possibility of such damage.

The authors, ptTheragnostic and MAASTRO clinic specifically disclaim any warranties, including but not limited to, the implied warranty of fitness for calculating the probabilities of outcomes for patients. The software provided hereunder is on an as is basis and neither the authors, ptTheragnostic nor the MAASTRO clinic have any obligations to provide maintenance, support, updates, enhancements or modifications.

By proceeding with use of the models, the user agrees that they have read and agreed with these terms.

This website is designed to inform physicians and provide them with probability scores for a number of outcomes. The models calculate the probability that certain side-effects, treatment outcomes and follow-up outcomes will occur. ptTheragnostic B.V. does not record prediction tool user outcome.

These models should only be used by physicians who are familiar with the complexity of treatment decisions in cancer treatment and should not be used directly by patients. We emphasize that the purpose of these models is to inform physicians and that the models should not be used for decision support. The models available on this website are not regarded as medical devices under the current MEDDEV guidelines from the European Commission.

The calculators which are provided are freeware for personal use only. They are not public domain software and may not be sold or used for commercial purposes. Permission to use and backup this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted. Permission to distribute this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted, provided that a reference to the following website and the entire License and Disclaimer are provided with all distributed copies: http://www.PredictCancer.org

The authors have made every effort to ensure that the information provided by this software is accurate and conforms to the methods described in the publications. However, the probability estimates published in the papers and which are estimated with these calculators may differ from those found in current clinical practice. In addition, a patient's prognosis may depend on other factors than those taken into account here. Thus, any decisions concerning patient care should not be based only on the use of these calculators, but should also take into account the patient's past history and other current patient and tumor characteristics. The model output supplements but does not substitute this individual clinical assessment. The creators of the PredictCancer website are not liable for clinical decision making that occurs between a physician and a patient.

As medical science is constantly changing and human error is always possible, the information contained in the prediction tools may be outdated, incomplete or incorrect. The authors, ptTheragnostic and MAASTRO clinic do not warrant the calculators' accuracy nor are they responsible for any omissions, errors or outcomes resulting from the use of these calculators. In no event shall either the authors, ptTheragnostic or MAASTRO clinic be liable to any party for any direct, indirect, special, incidental, or consequential damages, including lost profits, arising from the use of this software even if they have been advised of the possibility of such damage.

The authors, ptTheragnostic and MAASTRO clinic specifically disclaim any warranties, including but not limited to, the implied warranty of fitness for calculating the probabilities of outcomes for patients. The software provided hereunder is on an as is basis and neither the authors, ptTheragnostic nor the MAASTRO clinic have any obligations to provide maintenance, support, updates, enhancements or modifications.

By proceeding with use of the models, the user agrees that they have read and agreed with these terms.

This website is designed to inform physicians and provide them with probability scores for a number of outcomes. The models calculate the probability that certain side-effects, treatment outcomes and follow-up outcomes will occur. ptTheragnostic B.V. does not record prediction tool user outcome.

These models should only be used by physicians who are familiar with the complexity of treatment decisions in cancer treatment and should not be used directly by patients. We emphasize that the purpose of these models is to inform physicians and that the models should not be used for decision support. The models available on this website are not regarded as medical devices under the current MEDDEV guidelines from the European Commission.

The calculators which are provided are freeware for personal use only. They are not public domain software and may not be sold or used for commercial purposes. Permission to use and backup this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted. Permission to distribute this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted, provided that a reference to the following website and the entire License and Disclaimer are provided with all distributed copies: http://www.PredictCancer.org

The authors have made every effort to ensure that the information provided by this software is accurate and conforms to the methods described in the publications. However, the probability estimates published in the papers and which are estimated with these calculators may differ from those found in current clinical practice. In addition, a patient's prognosis may depend on other factors than those taken into account here. Thus, any decisions concerning patient care should not be based only on the use of these calculators, but should also take into account the patient's past history and other current patient and tumor characteristics. The model output supplements but does not substitute this individual clinical assessment. The creators of the PredictCancer website are not liable for clinical decision making that occurs between a physician and a patient.

As medical science is constantly changing and human error is always possible, the information contained in the prediction tools may be outdated, incomplete or incorrect. The authors, ptTheragnostic and MAASTRO clinic do not warrant the calculators' accuracy nor are they responsible for any omissions, errors or outcomes resulting from the use of these calculators. In no event shall either the authors, ptTheragnostic or MAASTRO clinic be liable to any party for any direct, indirect, special, incidental, or consequential damages, including lost profits, arising from the use of this software even if they have been advised of the possibility of such damage.

The authors, ptTheragnostic and MAASTRO clinic specifically disclaim any warranties, including but not limited to, the implied warranty of fitness for calculating the probabilities of outcomes for patients. The software provided hereunder is on an as is basis and neither the authors, ptTheragnostic nor the MAASTRO clinic have any obligations to provide maintenance, support, updates, enhancements or modifications.

By proceeding with use of the models, the user agrees that they have read and agreed with these terms.

This website is designed to inform physicians and provide them with probability scores for a number of outcomes. The models calculate the probability that certain side-effects, treatment outcomes and follow-up outcomes will occur. ptTheragnostic B.V. does not record prediction tool user outcome.

These models should only be used by physicians who are familiar with the complexity of treatment decisions in cancer treatment and should not be used directly by patients. We emphasize that the purpose of these models is to inform physicians and that the models should not be used for decision support. The models available on this website are not regarded as medical devices under the current MEDDEV guidelines from the European Commission.

The calculators which are provided are freeware for personal use only. They are not public domain software and may not be sold or used for commercial purposes. Permission to use and backup this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted. Permission to distribute this software for any non-commercial purpose, without fee, and without a written agreement is hereby granted, provided that a reference to the following website and the entire License and Disclaimer are provided with all distributed copies: http://www.PredictCancer.org

The authors have made every effort to ensure that the information provided by this software is accurate and conforms to the methods described in the publications. However, the probability estimates published in the papers and which are estimated with these calculators may differ from those found in current clinical practice. In addition, a patient's prognosis may depend on other factors than those taken into account here. Thus, any decisions concerning patient care should not be based only on the use of these calculators, but should also take into account the patient's past history and other current patient and tumor characteristics. The model output supplements but does not substitute this individual clinical assessment. The creators of the PredictCancer website are not liable for clinical decision making that occurs between a physician and a patient.

As medical science is constantly changing and human error is always possible, the information contained in the prediction tools may be outdated, incomplete or incorrect. The authors, ptTheragnostic and MAASTRO clinic do not warrant the calculators' accuracy nor are they responsible for any omissions, errors or outcomes resulting from the use of these calculators. In no event shall either the authors, ptTheragnostic or MAASTRO clinic be liable to any party for any direct, indirect, special, incidental, or consequential damages, including lost profits, arising from the use of this software even if they have been advised of the possibility of such damage.

The authors, ptTheragnostic and MAASTRO clinic specifically disclaim any warranties, including but not limited to, the implied warranty of fitness for calculating the probabilities of outcomes for patients. The software provided hereunder is on an as is basis and neither the authors, ptTheragnostic nor the MAASTRO clinic have any obligations to provide maintenance, support, updates, enhancements or modifications.

By proceeding with use of the models, the user agrees that they have read and agreed with these terms.


Description of the prediction tool for survival of stage III non-small cell lung cancer patients

This tool predicts the probability that a patient with stage III non-small cell lung cancer (NSCLC) will be alive at 2 year or 3 year post-radiotherapy treatment.

To which patients does this tool apply?

The tool is developed for stage III NSCLC patients. FDG-PET has to be used as a staging tool. Patients have to be treated with high-dose conformal radiotherapy alone or high-dose conformal radiotherapy combined with chemotherapy (sequential or concurrent). They have not undergone surgical treatment nor prior chest radiotherapy, nor have distant metastasis at the time of diagnosis.

How was this tool developed?

The prediction model is based on data of 548 NSCLC patients, treated at MAASTRO clinic with high-dose conformal radiotherapy alone or combined with chemotherapy (sequential or concurrent) and built using a stratified Cox proportional hazards regression analysis. The predicted outcome is 2 and 3 year survival post-radiotherapy.

The predictive mean matching algorithm was used for missing value imputation. The percentage of missing values was 13% for forced expiratory volume 1 s (FEV1), 1% for World Health Organization Performance Scale (WHO-PS), 5% for clinical T-stage, 8% for gross tumor volume (GTV) and 6% for number of positive lymph node stations (PLNS).

Variable selection was performed with a bootstrap procedure. First, it was determined how many variables should be included in the model by performing backwards variable selection for 100 bootstrap samples. Subsequently, backwards selection on the original data set was applied to identify which variables should be retained in the model.

The performance of the model is expressed as the AUC of the ROC. The maximum value of the AUC is 1.0, indicating a perfect prediction model. A value of 0.5 indicates that patients are correctly classified in 50% of the cases, i.e. as good as chance. The performance of the model on the training set was 0.65, corrected for optimism this value decreased to 0.62. Two datasets from NKI (Netherlands Cancer Institute) (n=174) and MSKCC (Memorial Sloan Kettering Cancer Center) (n=130) were available for external independent validation of the model. Application of the model to these datasets yielded AUCs of 0.58 and 0.60 respectively.

What information will you need?

  • Gender
  • Age at start of treatment
  • WHO-PS before start of radiotherapy
  • FEV1 before start of radiotherapy (forced expiratory volume in 1 second)
  • Clinical T-stage
  • GTV1 (volume of the primary tumor)
  • Number of positive lymph node stations (PLNS), assessed with FDG-PET, according to the Naruke map
  • Chemotherapy
    • No chemo
    • Sequential as standard protocol
    • Sequential given because a patient is not fit enough for concurrent chemo radiation
    • Concurrent chemo radiation
  • OTT (overall treatment time of radiotherapy, in days)
  • EQD2 (equivalent radiation dose, corrected for fraction size)

Journal articles that support this prediction tool

C. Oberije et al, A validated prediction model for overall survival from stage III non-small cell lung cancer: toward survival prediction for individual patients. Int J Radiat Oncol Biol Phys, 2015. pii: S0360-3016(15)00254-0. doi: 10.1016/j.ijrobp.2015.02.048. (published free online)